Why you can't compare Covid-19 vaccines

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महीने पहले

What a vaccine's "efficacy rate" actually means.
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In the US, the first two available Covid-19 vaccines were the ones from Pfizer/BioNTech and Moderna. Both vaccines have very high "efficacy rates," of around 95%. But the third vaccine introduced in the US, from Johnson & Johnson, has a considerably lower efficacy rate: just 66%.
Look at those numbers next to each other, and it's natural to conclude that one of them is considerably worse. Why settle for 66% when you can have 95%? But that isn't the right way to understand a vaccine's efficacy rate, or even to understand what a vaccine does. And public health experts say that if you really want to know which vaccine is the best one, efficacy isn't actually the most important number at all.
Further reading from Vox:
Why comparing Covid-19 vaccine efficacy numbers can be misleading: www.vox.com/22311625/covid-19-vaccine-efficacy-johnson-moderna-pfizer
The vaccine metric that matters more than efficacy: www.vox.com/22273502/covid-vaccines-pfizer-moderna-johnson-astrazeneca-efficacy-deaths
The limits of what vaccine efficacy numbers can tell us: www.vox.com/21575420/oxford-moderna-pfizer-covid-19-vaccine-trial-biontech-astrazeneca-results
Vox.com is a news website that helps you cut through the noise and understand what's really driving the events in the headlines. Check out www.vox.com.
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Emilian Stanev
Emilian Stanev 22 मिनट पहले
2 months later....the mayor was right o.O
iMoooDey घंटे पहले
the animation frames are so low that the look bad 1:30
MIN DAYSUGA घंटे पहले
The numberless nation randomly zip because draw substantially warn except a holistic peru. honorable, tense skin
Lydia Derhake
Lydia Derhake 4 घंटे पहले
Still, the point is that vaccines don't protect you against a virus, but only strains of the virus. This is true of the flu shot. It's true of COVID. You have the potential for a lower likelihood of having the virus, but ONLY if it's the strain in the vaccine.
ich du
ich du 5 घंटे पहले
A big thanks to Germany! Biontech FTW! :-)
Arjun Kelaiya
Arjun Kelaiya 6 घंटे पहले
Great info!
Chandan Kumar Mishra
Chandan Kumar Mishra 8 घंटे पहले
now...this is called an explanation...too good content and presentation...well done VOX...
norceros xD
norceros xD 8 घंटे पहले
What about the vaccines produce in China and India??
Audrée & Jamie
Audrée & Jamie 8 घंटे पहले
Great information that’s explained clear and concise. Thank you 😊
Lord Friki
Lord Friki 8 घंटे पहले
A good plan executed now is better than a perfect plan executed next week.
るなめりあ 11 घंटे पहले
working at vox sounds like a science project for adults
Green Thumb
Green Thumb 14 घंटे पहले
Mark of the beast. In the Bible is says never pierce the body for I am God
Tomás Iriarte
Tomás Iriarte 14 घंटे पहले
Mr Meme
Mr Meme 15 घंटे पहले
It's a J&J video to defend It's version because it's the lowest efficacy. Why wasn't it tested in the US is probably because they wouldn't pass the stricter guidelines and they could cheat lie elsewhere. Just like people are judged by their history so should companies. J&J history is shady big-time.
Janitha Jayasanka
Janitha Jayasanka 15 घंटे पहले
how about the chinese sinopharm ?
Nathaniel Smith
Nathaniel Smith 15 घंटे पहले
Gawd vox’s videos are good when they stay away from politics
ahpong 16 घंटे पहले
Excellent infographics and narration. Easy to understand. 7 minute time debunks all the Efficacy myths.
This is super crystal clear explanation. Thank you
xXScythianUAXx 16 घंटे पहले
all this topic of pandemic is very high on speculations and politization all the time
Brett Yoss
Brett Yoss 18 घंटे पहले
There is no such thing as a cure... The only reason you want a vaccine is so that you hope to not have as harsh of symptoms... It doesn't make you immune.. Nor does it keep you from spreading it to others so I would enjoy it if you actually looked up what a vaccine does and doesn't do before you act like its a CURE... which doesn't and has never existed ever.
koike28 19 घंटे पहले
Covid pandemic - the biggest lie in the history of mankind.
Combo Breaker
Combo Breaker 21 घंटे पहले
They forget something. How many died from Bloodclots from A/Z and, Jonson vaccines
Beulah West
Beulah West 22 घंटे पहले
The heavenly heavy hellish consonant consistently book because skin extracellularly scrape midst a belligerent pantyhose. normal, soft shampoo
Nathan Wuerch
Nathan Wuerch 22 घंटे पहले
Why you can't compare Covid-19 vaccines
Hammad Shahid
Hammad Shahid 23 घंटे पहले
Can someone explain if I am not understanding this, but... isn't it inhumane to give people the placebo and lead them to their deaths?
Tomás Iriarte
Tomás Iriarte 14 घंटे पहले
They sign a contract where they accept that they may be receiving the placebo instead from the vaccine. All vaccines need to go through a testing process, and people offer themselves voluntarily to participate in this process, accepting that they may or may not get vaccinated if they decide to participate. Remember that this placebo thing is only for the testing phase.
Opochtli दिन पहले
Thanks !
bonuskind दिन पहले
and It's "Biontech / Pfizer"!!!!! not "Pfizer / Biontech", just saying! development was by biontech
Omkar Pathak
Omkar Pathak दिन पहले
It's not all true about efficacy and infection relationship. I am from india I can see atleast 4 people who get inflected and unfortunately died after getting vaccinated like 2 dose + 20 days They taken Astra Zenica vaccine. So either we need to update the vaccine as per new strain or need to rethink about efficacy rate.
Prim Css
Prim Css दिन पहले
I have a question for everyone.What do you think about Sinovac vaccines?
Baheth Al khazraji
Baheth Al khazraji दिन पहले
Thank you very much for this wonderful effort. Continue this useful, distinctive performance.
Zayda Cortez
Zayda Cortez दिन पहले
Wow I’m so happy I watched this. I’ve been living in ignorance
Zayda Cortez
Zayda Cortez दिन पहले
Abishe Sunfoil
Abishe Sunfoil दिन पहले
Excellent video I hope everyone understood about the efficacy of vaccines
Sam Tan
Sam Tan दिन पहले
Wrong ...what is the fact of percentage we saw?
Max -x
Max -x दिन पहले
Is astra good
Yiannis Hylton
Yiannis Hylton दिन पहले
thanks for the info....before you are so confident. should we not wait for the actual manufacturer studies to be completed first?? 22-23. how are you so sure on your data when the data is not complete.
Laurens Boers
Laurens Boers दिन पहले
why is it called jonhson&johnson its developed in the netherlands and the name sould be jansen&jansen when the are side affects then the name is jansen
Oinam Thoujal
Oinam Thoujal दिन पहले
Still we trust Spunik-V, even the WHO under some hidden political pressure not clear. Spunik-V was first vaccine to develop and test.
James P
James P दिन पहले
Thank you for this! I feel the media has poorly explained the distinction between protection from death, and protection from catching COVID. This is the first time I feel confident in understanding what it means.
Amerti TheBird
Amerti TheBird दिन पहले
Guys I have a question. Does a fit person have a lower chance to be in a severe side effect than average people when getting the vaccine?
BeLocal SingaporeFoodWriter
BeLocal SingaporeFoodWriter दिन पहले
I agree getting vaccinated you will realise the virus is most place where international human meet. Your body seems to recognise some light symptoms for few days. But it doesn’t make you so I’ll to a flu or fever or cough
Huskie दिन पहले
it's JANSSEN, please
Agnieszka Sciog
Agnieszka Sciog दिन पहले
Shiiiii Detroit dodged a bullet
qwerty12345470 दिन पहले
So are we just going to stay locked down forever? When does it end?
ZERO M. दिन पहले
1-2 years with mask then you have freedom but maybe in some month we can live normaly but with mask only
WalterLiddy दिन पहले
Here's my question - when they did the J&J trials, why DIDN'T they redo the Pfizzer and Moderna trials for contrast? In fact, why not use them instead of the placebo? You'd still get a comparative result, but you wouldn't be sending half your patients off at greater than necessary risk.
thund3r दिन पहले
I am not getting vaccinated because I have a strong immune system, I barely catched a cold in my life of 29 years.
ZERO M. दिन पहले
Haha then you cannot do anything in the future, this is why they force you to get a vaccine because people want to go out, people want to go vacation and so on
TV Viewer
TV Viewer दिन पहले
These vaccines don't vaccinate. They are there just to hurt you.
kk दिन पहले
Great video. Thanks definitely cleared some misunderstandings I had and made me understand vaccines better! Thank you
Sparkling Glitter
Sparkling Glitter दिन पहले
Tennessse Timmy
Tennessse Timmy दिन पहले
Wow what a great video I learned so much about vaccines! This comment was brought to you by Johnson & Johnson
A N दिन पहले
Yes, take any shot you can. Having said that, isn't the efficacy of Pfizer still quite higher than J&J even against variants? Like 70%-90% in tests. (which is no reason to not take it, just pointing that out)
sudarsan ramakrishnan
sudarsan ramakrishnan दिन पहले
well illustrated and well said.. "best vaccines are the ones you are offered".. our society is so used to choosing everything think with so many options that we always compare even if it means life of death and only want the best.. there is no need to get best vaccine one year from now while you can get the second or third best, right now and stop being the bridge for that nasty virus..
Shetu Raj
Shetu Raj दिन पहले
How can you not mention Covishield and Covaxin from India? They were supplied to 65 different countries by India
Bill Kong
Bill Kong दिन पहले
Sputnik V is still the best just because of its name
J Mojo
J Mojo 2 दिन पहले
I would like someone to show me the proof how effective these vaccines are! Did you know that COVID-19 vaccine manufacturers define “effectiveness” as “reduction in risk of symptoms such as a fever, cough or sore throat?” Heck, on the CDC’s own website, they state “There is some evidence that vaccination may make illness less severe.” The term “effective” was not defined as preventing viral infection or spread of the (SARS-CoV-2) virus to others. This is the reason why vaccinated individuals are still recommended to wear facemasks, socially distance and avoid large crowds.
crystal Sandoval Cantu
crystal Sandoval Cantu 2 दिन पहले
Why don’t y’all ask google who is the most powerful Dr in the world and get a kick out of that response 🤣
Bianca Roma Ciupe
Bianca Roma Ciupe 2 दिन पहले
I've been vaccinated on 8 mars with astrazeneca, now I am isolated being direct contact to a Cov + person, sick of UK variant. It's been 9 days now, I cough, lost my taste and smell, but no fever, and I don't feel sick ! and I feel good that I 've done the vaccine! the unvaccinated contacts are much worse now!
BadmintonLegends 2 दिन पहले
When one should take vaccine after recovering covid..??
Pičkin Dim
Pičkin Dim 2 दिन पहले
The Cuban vaccine is the best
tomstarott 2 दिन पहले
Excellently explained about efficacy! Just remember the other consideration is safety and unknown long term side effects of these chemicals approved by FDA so far only for "emergency use".
Marius -
Marius - 2 दिन पहले
Great video!
• star_dreamer •
• star_dreamer • 2 दिन पहले
I love watching/listening to you guys videos while doing, anything. They’re informational and I like informational videos =)
ASTRO 2 दिन पहले
Feels bad for those who got a placebo and died
Dimeo 2 दिन पहले
i'm not going to be mean to you, I would rather have a discussion. Lets start with this, could you offer me a reliable source of these deaths?
km o
km o 2 दिन पहले
Really all are still new vaccines 6 month and under they have been used not counting the trials and the Astra Zeneca one proves the trials can’t tell you everything. 0 deaths in trials of them yet now there has been a few deaths caused by it. Still far less risk than the virus itself so it is still being used but in U.K. and maybe other countries it’s only being used in older people to balance the risk of the virus. I’ve been lucky. Got called to get vaccine end of February which could have been the Astra Zeneca or Pfizer I’m under 40 and healthy so no idea why I was put so high up to get vaccine and got the Pfizer. Only days before my 2nd dose yesterday U.K. decides anyone under 40 should get a different vaccine to the Astra Zeneca. So I should have got Pfizer which I did but at time I could have ended up getting Astra Zeneca.
Piyush Asrani
Piyush Asrani 2 दिन पहले
I'm glad some people are trying to get everyone aware.
Beatern Plays
Beatern Plays 2 दिन पहले
Just shut up. You can't tell me why I can't compare them, when research shows that some vaccines don't even contain the deactivated form of the virus in it. How do you inoculate people without putting the agent you wish to build immunity against in the vaccine? You are all playing with humans. No longer tho.
Dimeo दिन पहले
@Nam thank you for the further input. You mentioned some things I didn’t. Have a nice day 😊 edit: never mind, mine was too long and was marked as spam :( the comment above me does the job though
Nam दिन पहले
@Beatern Plays You're right that the three US Vaccines plus some abroad (AstraZeneca, J&J, Pfizer, and Moderna) don't use a weakened COVID virus - weakened COVID virus particles are used in vaccines like the Sinopharm shot. The mRNA (Pfizer/Moderna) and Adenovirus vector (Astrazenenca/J&J) do cause the body to produce the spike protein, but these are precisely what's needed to get an immune response! Instead of your body's cells recognizing the protein on the weakened COVID virus, they can use the spike protein produced from the mRNA or adenoviral vectors. Both create immunity and "clue in" your body's immune cells for future antibody and killer-T cell immune responses (As an analogy: if you saw a photo of an apple versus a whole real apple, you'd still recognize it. The important part is that all vaccines eventually induce an immune response)
Beatern Plays
Beatern Plays 2 दिन पहले
@Dimeo Hi, I'd like that too. Thanks for dropping in, hope you're doing well :) Through my research about this, supposedly the vaccine has some sort of protein of the virus but not the virus itself. The info suggested it could possibly cause a reverse effect of building immunity. Rather fooling the immune system to fight itself. We can go more in depth in some chat service if that's a thing. I am curious to speak with you and share experience Hear from you soon :)
Dimeo 2 दिन पहले
I would like to have a healthy dialogue with you. I’m curious if you know how the mRNA technology works in the vaccine? I am personally aware of what it does but I just want to know if you do. If you’re unsure I would be very willing to explain it to you as long as you’re willing to have a discussion :)
Aruce lee
Aruce lee 2 दिन पहले
pfizer kills
Dimeo दिन पहले
@Ghost Of James Doakes I tried looking that one up, didn’t find anything resourceful. Would you like to try again? I’m genuinely very curious to find something concrete on this :)
Ghost Of James Doakes
Ghost Of James Doakes दिन पहले
@DogeSoup source: stop being a doubtful zombie
DogeSoup दिन पहले
@Ghost Of James Doakes source: dude just trust me, and facebook
Dimeo दिन पहले
@Ghost Of James Doakes I'm asking because I have actually looked for it myself, however I haven't been able to find statistics from reliable sources. I figure if its so easy to find, people should be able to guide me in the right direction. Am I wrong? :)
Ghost Of James Doakes
Ghost Of James Doakes दिन पहले
@Dimeo how about you do your own independent research instead of acting like the truth isn't obtainable on a search engine that isn't google. There have been more vaccine deaths this year alone than in the last 20 years.
Michal Lucki
Michal Lucki 2 दिन पहले
Oh come on. Nurses and doctors get Pfeizer and this speaks for itself.
Kody Hall
Kody Hall 2 दिन पहले
How much did J&J pay for this?
Blue Bird
Blue Bird 2 दिन पहले
Well DONE Vox. This definatly taught me. LOVE it.
SuperEman500 2 दिन पहले
American vaccines= trash Sputnik= best, long live Mother Russia 🇷🇺
trickshotmonkey 2 दिन पहले
Shouldn’t we check, if a person has natural antibodies before administration of the vaccine? Will this help people, who have no antibodies to receive the vaccine first?
Craig Phd
Craig Phd 2 दिन पहले
What you say does make sense. The point of vaccines is to create anti-bodies. If you have had the virus and fully recovered, you have the anti-bodies. Bear in mind that you produce anti-bodies for that particular variant of the virus you contracted. The same as the vaccines do. Do the anti-bodies work on all, some, or none of the variants? research is continuing in that area. From a medical standpoint, if you can verify you have anti-bodies, with at least the same loading as that given by the vaccines, you don't need a vaccine. We also do not know how long anti-bodies last with absolute certainty. What is known, is that someone vaccinated 6 months ago, still has the anti-bodies. As do those that contracted the virus and produced their own ant-bodies. However i think this is a logistics/cost problem. Prior to being given a vaccine, everyone would need a test to show 100% that they have anti-bodies. To show 100% would entail laboratory analysis. Best case, with massive resources, this would take over 24 hours. The time and cost would be prohibitive. You could of course pay for your own anti-body test, just make sure it is accurate. One of the PCR type tests (There are 3), which tests for anti-bodies, is 85% accurate. Thats the long answer to your 2 questions. The short answer to the first question is Yes. The short answer to the second question is , potentially, Yes.
M C 2 दिन पहले
so, at the end of the day, Russians make the best vaccines . .
Alex Roblox
Alex Roblox 2 दिन पहले
Pavel Scott
Pavel Scott 2 दिन पहले
I don't believe they're experimentally .... there are no approved clinical trials ... and no one knows what will happen in a few months or a year.
Dimeo 2 दिन पहले
I hope me and you can have a healthy discussion about this. I personally believe you have received inaccurate information and I’m willing to clear things up for you if you would allow me :)
New Eden
New Eden 3 दिन पहले
J&J lost all credibility, they are a disgrace, and should face criminal charges
Lost 3 दिन पहले
this video was sponsored by Johnsond and Johnson
Anony grazer
Anony grazer 2 दिन पहले
Marcelo Salame
Marcelo Salame 3 दिन पहले
The argument that we cannot compare them because they were tested on different "covid waves" is not very logical. If one was tested in an environment that people had more exposure to the virus, both the placebo and vaccinated groups would have more positives, proportionally, which would keep the percentage balance the same, therefore, generating the same (or very close) efficacy rates. The argument that all vaccines are 100% protective to severe cases, that I agree.
Jack Ward
Jack Ward दिन पहले
Well that wasn’t there argument
tanmay rao
tanmay rao 3 दिन पहले
Vox dosent understand how percentages work
Tommy Mori
Tommy Mori 3 दिन पहले
Pass on all the above. Ill take my .000003% chances lololololol. My cure? I turned off CNN and went outside.
DogeSoup दिन पहले
The fatality rate in elders above 80 is around 45% and I don't think that's better than getting injected 2 times and not dying
dhenryviii 3 दिन पहले
So the side effects matter the most in choosing which brand of vaccines to take.
Kullarat Kuntawong
Kullarat Kuntawong 3 दिन पहले
This is very helpful.
Andrew Koay
Andrew Koay 3 दिन पहले
Perhaps vaccine “Efficacy Rates” needs to be challenged to reflect the infections that we see now despite having completed vaccinations earlier?
koukimonzta 3 दिन पहले
I got JnJ and I am stronger than Godzilla
DogeSoup दिन पहले
Well done
AdizxA 3 दिन पहले
Sinovac: Am I a joke to you?
Megaseawolf 3 दिन पहले
03:13 The Pfizer/ BioNTech trials included 150 clinical sites: The US, Germany, Turkey, South Africa, Brazil and Argentina.The info here is somewhat inaccurate 🤔
TheFelltimber 3 दिन पहले
pretty helpful
gryphon blaze
gryphon blaze 3 दिन पहले
What about the sinovac vaccine is it any good?
Youssef Alamood
Youssef Alamood 3 दिन पहले
If your gen modification therapy is so good why do you need to force it on people and why do you need this much marketing ? who pays for this videos ?
Youssef Alamood
Youssef Alamood दिन पहले
@DogeSoup rewrite your question again please.
DogeSoup दिन पहले
@Youssef Alamood Still didn't answer my question because you can't.
Youssef Alamood
Youssef Alamood दिन पहले
@DogeSoup Talk about your genes, I will not take the vaccine.
DogeSoup दिन पहले
Ok, so. In a hypothetical world, the vaccines modify your genes but reduce the rate of infection by 96%. What is the problem with that? Does the term "Gene Modifying" sound too scary to you? Because as all I know dihydrogen monoxide contains a lot of parasites including brain-eating amoeba and it still is not classified as toxic!
Joe D
Joe D 3 दिन पहले
For all the people who rushed out to get vaccinated, please keep us updated after a year. I would love to know if there are any new issues with your health like cancer or something different. Thanks.
Dimeo दिन पहले
@Joe D This is the second comment I am making, my first one you are not able to see because INcds marked it as spam for being too long :( Its a shame because I had some valuable info in it. I will instead lead you to a resource that you can check out for answers you are looking for. Look up 'professor Dave explains vaccines'. I recommend you watch the whole thing but I get it, people are busy these days. Watch the last 9 minutes of the video, it will clear up skepticism about the speed at which the vaccine was created. I hope it helps :)
Joe D
Joe D दिन पहले
@Dimeo sure, when I was 15 years old I was giving a flu vaccine and and about 3 to 4 weeks later I became paralyzed. I believe they called it GBS. I just understand why would anyone would rush to take something that hasn’t been fully tested and that’s been created in less than 3 months. Just because you don’t hear anything from the media doesn’t mean there’s the vaccine is safe to take. Personally, I would wait 2-3 years before taking this vaccine. Enough time to know the vaccine has gone through enough testing.
Dimeo 2 दिन पहले
Would you be willing to have a healthy dialogue about things in regard to the vaccine? If there is anything you’re skeptical about or unsure of I am willing to share what I know so we can both learn something :)
DJ Barry
DJ Barry 3 दिन पहले
I know republicans are mad after watching this video
Young Min Ju
Young Min Ju 3 दिन पहले
astra has too much side effet
Amy S
Amy S 3 दिन पहले
So in other words, which vaccine are you willing to trial and be a Guinea pig for...
Dimeo 2 दिन पहले
Would you be willing to have a discussion surrounding the safety of the vaccine? I reckon it would benefit us to have a healthy dialogue to clear anything up that you may be skeptical/unsure about when it comes to the vaccine. Let me know if you’re open to it :)
Christopher Bhagwandin
Christopher Bhagwandin 3 दिन पहले
thanks for this
Mohammad Abdullah Al Mamun Ashik
Mohammad Abdullah Al Mamun Ashik 3 दिन पहले
it's a good video.
MAGA 3 दिन पहले
wonder how they work if you mix types for second dose ?
desert knight s
desert knight s 3 दिन पहले
This is a big lie , I've seen cases of vaccinated people infected and died from corona
desert knight s
desert knight s दिन पहले
@Dimeo simply , they took vaccine and got strokes or other issues , two of them
Dimeo दिन पहले
@desert knight s I must ask, how are you sure that it was from the vaccine? What details can you give me, if any. If you’re uncomfortable though I understand.
desert knight s
desert knight s दिन पहले
@Dimeo from my family unfortunately
Dimeo 2 दिन पहले
I would like for us to have a healthy discussion about this. I’ll allow you to take the first step, could you please provide an accurate source of these infections/deaths? :)
Brendan Raz
Brendan Raz 3 दिन पहले
This explanation should be translated to many languages to make lay ppl understand,just like me. Thank you God bless 🙏🙏
Shubham Stan
Shubham Stan 2 दिन पहले
Sasha Van Niekeerk
Sasha Van Niekeerk 3 दिन पहले
What is a placebo?
MAGA 3 दिन पहले
means no vaccine,, ie water etc
Naresh Chandiramani
Naresh Chandiramani 3 दिन पहले
I personally know 5 persons who died after first dose of Astra Zeneca. The 2nd dose being after 2 months, in India where getting vaccines is like a lottery
Dimeo 2 दिन पहले
I’m curious, willing to have a discussion about this and listen to you. I would like to pose a question to you though and I don’t mean it in an aggressive way at all, but how do you know it was because of the vaccine? How do you know that it wasn’t some other outside source?
Maria Quiet
Maria Quiet 2 दिन पहले
There's a reason I don't trust word of mouth. Anyone can say anything online.
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